VISDB Viral Integration Site DataBase

VIS ID

TVIS10007960

Fusion event

HBV-DEPDC1B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1818

Orient

-

Integrated sequence

GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT

Chromosome

chr5

Cytoband

q12.1

Reference genome

Start

End

59991515/60695688 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-361-5p ; hsa-mir-4282 ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-95-5p ; hsa-mir-455-5p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-10397/Upstream/991985; hsa-mir-103a-1/Downstream/11473779;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/802007, chr5-CpG: 87/Downstream/3859

Upstream sequence

tgacacttagttgcctcatcctgaaaatttcaatgaaaacttgccaccttactttgctgtgatataacaaaagtaggaatgtttttaactcataaactgt

Downstream sequence

tgttcctgtgtaataccatacagttgtcattacagtcaattaataccaagtataaatccctggtaggacaaggcccctgtcttctttGTAAGGGAATGTG