VISDB Viral Integration Site DataBase

VIS ID

TVIS10007962

Fusion event

HBV-FAM172A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1980

Orient

-

Integrated sequence

GTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCA| |GTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTC

Chromosome

chr5

Cytoband

q15

Reference genome

Start

End

93414823/94079118 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-330-3p ; hsa-mir-218-5p ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6835-3p

Nearest miRNA

hsa-mir-10397/Upstream/458330; hsa-mir-103a-1/Downstream/2000020;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/457484, chr5-CpG: 41/Downstream/32130

Nearest cancer related gene

FAM172A(TSG, No orient, 0)

Upstream sequence

NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNtaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccct

Downstream sequence

CTTGGGTTTCCAAGACTATATTGAAAATAATTATAATGGAACTTAATTTTTGGACATAAGTTATACTTACATTCATTTCATTATATTTACATTCCTTTAC