Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007974
Fusion event
HBV-ZCWPW1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1744
Orient
-
Integrated sequence
CAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTG| |GGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCAT
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
End
100011365/100413742 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/57021; hsa-mir-10399/Downstream/454294;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/77278, chr7-CpG: 199/Downstream/14439
Upstream sequence
ccctaaacctaaccctaaccctaaccctaacaaccctaaccctaaccctaaccctaaccctaacaaccctaaccctaacaaccctaaccctaaccctaac
Downstream sequence
TTTAATATAAATTCACtttttttcttttttatagagacgggggtctcactatgttacccaggctagtctggactcaagcaagcttcctgcctcagcctcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.