Basic Information
VIS ID
TVIS10007975
Fusion event
HBV-chr7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2614
Orient
-
Integrated sequence
CTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAAT| |GAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAAC
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
89495856/89866542 (Hg38)
End
89495856/89866542 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/13951273; hsa-mir-10399/Downstream/2337473;
Nearest TSS
ENST00000635602/Upstream/422568; ENST00000475789/Downstream/256348;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1106573, chr7-CpG: 98/Downstream/252036
Nearby gene
ZNF804B(-529510) ; DPY19L2P4(+252858) ;
Upstream sequence
atgcacacaaattttttaaaccataaaatactacgtttctattatgtatacataacatacataatatacagacagactaaacccacataggaataacaaa
Downstream sequence
tttttgcatacacaattcaatatcatatagatgttaatctttgccTGCACACGCATAAGCTCAGTTtcctgcttattgtctgaaatccttctttcgacac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate