Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007979
Fusion event
HBV-RGS20 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
998
Orient
+
Integrated sequence
TTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGA| |ATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTT
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
Start
End
54781774/53869214 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-124-1/Upstream/10972939; hsa-mir-10400/Downstream/7845574;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/25597, chr8-CpG: 92/Downstream/7807
Upstream sequence
gaatgaacaggaggaactaccaaacacttttaaaaccatcagatctcctgagaactcacttactataatgagaacagcatggggaagaccacacccgtga
Downstream sequence
GTTTATTTCATGTTTGTTTTTCTTTTTAGTTAGCTAGCAAATATAAAAAGTGGGGAGAAAGCACAGGTAGATCTTGGAATCTTAGGACTTTGGCACATGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.