C12orf71 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007994
Fusion event
HBV-C12orf71 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
753
Orient
-
Integrated sequence
CTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGG| |TATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAA
Host Sequence
Chromosome
chr12
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
27236720/27083787 (Hg38)
End
27236720/27083787 (Hg38)
Orient
+
Location type
Intronic
Target gene
C12orf71
Nearest miRNA
hsa-mir-1244-3/Upstream/1209708; hsa-let-7i/Downstream/15239913;
Nearest TSS
ENST00000382841/Upstream/1273; ENST00000434385/Downstream/77479;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/60877, chr12-CpG: 67/Downstream/160262
Nearby gene
C12orf71(-1265) ; STK38L(+160358) ;
Upstream sequence
TTCTTATTAATGCtaaataaatctgtaataaacccgcttttccataaatctttgactatgtctcttatttttctatatgtaggattaatggaccaaaccc
Downstream sequence
cataaatatattaaagtcttgtggtagttgataccaaattactttccagaaggttTTGGTATTTAGATGCCCATCCTCCCACCGTCTGATGACACTGTTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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