VISDB Viral Integration Site DataBase

VIS ID

TVIS10008022

Fusion event

HBV-FBXO42 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2356

Orient

+

Integrated sequence

TTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGAC| |GAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTA

Chromosome

chr1

Cytoband

p36.13

Reference genome

Start

End

16675599/16349104 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-1281 ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-627-3p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p

Nearest miRNA

hsa-mir-12136/Upstream/3770081; hsa-mir-101-1/Downstream/509845;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/111800, chr1-CpG: 52/Downstream/2975

Upstream sequence

GTTTGTTGCCTGTGTATATGACTCATATAGAAAGGTTTTCCCAAGACTGCTGGATTTTTGAGAATGCAGAAGCCATAACTGGGGCATACTGTGTGGGAAC

Downstream sequence

TGTCATGACAGTGAATGAATAAAAGGGGAAAAGAACCCATGACAGAATTTTTTTTCAAGTTTTTATAAAAAGCAAGTCACTCACTAAAGGCAGACTCTGC