Basic Information
VIS ID
TVIS10008024
Fusion event
HBV-LOC105373277 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1826
Orient
-
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
End
248687705/248524404 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/1322344; hsa-mir-3124/Downstream/301973;
Nearby gene
OR2G6(-1807) ; OR2T29(+34140) ;
Upstream sequence
TTTAACAAAAACGAGGGAAAAGAAGCCTGGTTAAATTTGTCTTCTAGGATATTCTTATGTGATTTTCCTCCTCCAGTAATGGAGAGGAGAGTTGGGAACT
Downstream sequence
GAGCAGAACATGCTGAGGAGCACATGTTTTTATTTACAATATGCAAGTAGAGAAGTAGTTCTACAGGAAGCGTCACATGTACAAATGCATTATTCCTGAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate