Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008027
Fusion event
HBV-ABCD3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
Start
End
94983369/94517813 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/670902; hsa-mir-11399/Downstream/25889;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/98967, chr1-CpG: 93/Downstream/23468
Upstream sequence
GAAAAGCCATTTTGGTTTTCCTTAACTAAATGATAAATGTACCCCTCTCAGTCTGCAGTATTGAGTTGTTTAAAGTATATGTGCAGTCTTGCTTACAAGG
Downstream sequence
AGGGGTTACCATGTATCACACCTAATCTTCCCAATGTTTGGGATATTAAAACACAAAGTCCTTAACATGCCAGGCTCAAGGTCTTATAAGAGTTCTAGAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.