VISDB Viral Integration Site DataBase

VIS ID

TVIS10008030

Fusion event

HBV-ARHGAP42 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2359

Orient

+

Integrated sequence

GTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAG| |GCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTC

Chromosome

chr11

Cytoband

q22.1

Reference genome

Start

End

100815062/100944331 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-28-5p ; hsa-mir-222-3p ; hsa-mir-138-5p ; hsa-mir-376c-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-4299 ; hsa-mir-3692-5p ; hsa-mir-4633-3p ; hsa-mir-6071 ; hsa-mir-6500-5p ; hsa-mir-587 ; hsa-mir-6131 ; hsa-mir-3185 ; hsa-mir-133a-5p ; hsa-mir-93-3p ; hsa-mir-885-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-4511

Nearest miRNA

hsa-mir-10392/Upstream/4602805; hsa-let-7a-2/Downstream/575489;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/256661, chr11-CpG: 170/Downstream/182968

Upstream sequence

TTCTAAGGAATAAGATGCAGGTGGGAATACTATAAGCTTCTTTCAGCCAACTAAGTTTAATGCCTCCAGGATGCCTCCTGTGTGCAAAGCACTGTTCCGG

Downstream sequence

GTATTCTTAGCCCAAAGTATTGGAAGAGATATAAATGTCGTGAATCTAAGTGTataatttaagtttacaataagaatgggtatgcttcttgctctctgct