NELL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008031
Fusion event
HBV-NELL1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1021
Orient
+
Integrated sequence
ACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGC| |TGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTT
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
21021630/21000084 (Hg38)
End
21021630/21000084 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
NELL1
Nearest miRNA
hsa-mir-210/Upstream/1240001; hsa-let-7a-2/Downstream/2419021;
Nearest TSS
ENST00000527297/Upstream/64388; ENST00000534263/Downstream/262486;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/329785, chr11-CpG: 88/Downstream/1192542
Upstream sequence
GTGTGTGTCTTTGGATGGGGATGTCTCAGAGCACTAATAGATGATGTTCCTCAGATCCACCAAGGGTAAATAAATGGAGTTGAACAAAAGGTGTTGGCAA
Downstream sequence
TGATTGACTAAATCACAGTGAAAGATGTGGATCTGGCCTTGGAAAACTTTTCTACTTAGCTGACATTCTTAGCTATTGTTTGACCTTGAATAAGAATCTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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