hsa-mir-4753-3p _LIHC.png
hsa-mir-1304-5p _LIHC.png
hsa-mir-892b _LIHC.png
ADIPOR2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008032
Fusion event
HBV-ADIPOR2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2422
Orient
+
Integrated sequence
TCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCA| |GAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATC
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
1866008/1756842 (Hg38)
End
1866008/1756842 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADIPOR2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-124-3p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-202-3p ; hsa-mir-1236-3p ; hsa-mir-1304-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4768-5p ; hsa-mir-6515-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4264 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-150-5p ; hsa-mir-4704-3p ; hsa-mir-3613-3p ; hsa-mir-186-5p ; hsa-mir-548c-3p ; hsa-mir-3130-3p ; hsa-mir-4717-5p ; hsa-mir-4753-5p ; hsa-mir-6768-3p ; hsa-mir-3658 ; hsa-mir-3119 ; hsa-mir-549a ; hsa-mir-3678-5p ; hsa-mir-892b ; hsa-mir-127-5p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4753-3p ; hsa-mir-6516-3p ; hsa-mir-942-5p ; hsa-mir-4797-3p ; hsa-mir-3121-5p ; hsa-mir-501-5p ; hsa-mir-4793-3p
Nearest miRNA
hsa-mir-3649/Upstream/96462; hsa-let-7i/Downstream/5206857;
Nearest TSS
ENST00000382841/Upstream/65679; ENST00000543456/Downstream/3887;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/65269, chr12-CpG: 125/Downstream/39269
Upstream sequence
agagatgatgtcacttgaaacagcatggtgggagcagcagaaatggagggaaatggttggattctggatatattttgtgggtcaaatcaacaagacttcc
Downstream sequence
tgatggattagctgtagagtgaggaaaatagaggaatcaaggctgattctctgagctgaactgaaatggtaaagcaagagggaagagcgggtttaaggta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate