Basic Information
VIS ID
TVIS10008042
Fusion event
HBV-chr17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1731
Orient
-
Integrated sequence
ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
End
21989716/22490387 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/3145813; hsa-mir-10226/Downstream/4803523;
Nearby gene
FLJ36000(-76646) ; MTRNR2L1(+32721) ;
Upstream sequence
ACCTGAGAGGGGCTGTGAGGCTCTGAGCAGGAGAGAGACTTGCCCAAAGGCCAAAGACAGGGAGGAGTAGAGTCTAACATGAGTACAAGATTGACTAGGA
Downstream sequence
CCATCGTTTATCTCTTTACACAGGAACAGGAGGAACTTGAGGCAAGGAAGGGCTATATAAGATGCAGTCCCCTCCCTGCAGGGGCCAGCTTGGTGCTGGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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