VISDB Viral Integration Site DataBase

VIS ID

TVIS10008045

Fusion event

HBV-KIAA0355 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1879

Orient

+

Integrated sequence

AGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGC| |TGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTC

Chromosome

chr19

Cytoband

q13.11

Reference genome

Start

End

34747451/34256546 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-3p ; hsa-mir-149-5p ; hsa-let-7e-5p ; hsa-mir-3687 ; hsa-mir-3157-3p ; hsa-mir-8075 ; hsa-mir-18b-3p ; hsa-mir-4708-3p ; hsa-mir-93-3p ; hsa-mir-451b ; hsa-mir-124-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p

Nearest miRNA

hsa-mir-10395/Upstream/13857192; hsa-let-7e/Downstream/866154;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/1247, chr19-CpG: 56/Downstream/102620

Upstream sequence

gaggcgaaggttgcagtgagccgaggtcgtgccactgcgctccagcctgggcaacagagtgagactccatctcaaaaaaaaaaaaaaagaaaTTCATGTT

Downstream sequence

TGCGTCTCATCGTTTCATGGTTTTATTTTTTTGCCTTTAGTCTACCTAAAATTCATTCTTGGTTTAAAATATGAAATATTTTGTAAATGGCTAGTCAGTT