VISDB Viral Integration Site DataBase

VIS ID

TVIS10008047

Fusion event

HBV-SLC5A7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2316

Orient

+

Integrated sequence

TTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCT| |ATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGC

Chromosome

chr2

Cytoband

q12.3

Reference genome

Start

End

108628903/108012447 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-3p ; hsa-mir-323b-3p ; hsa-mir-5589-3p ; hsa-mir-5692a ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-3941 ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-1285-2/Upstream/5580081; hsa-mir-10b/Downstream/1129043;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/25436, chr2-CpG: 39/Downstream/436606

Upstream sequence

ACTAAAGCACTTCTTTTCCAAAAATACTTCTGCAACTCATGAACAAAATGAAGTTAACTTAGTGTTTAGCATTAAAAATAAAAGTTGTACCTTGACCCTA

Downstream sequence

GAATTCCTTTTATAAGATTTAATTGTAATTGTCTCAAAGCATCAAATAATACATCTTTATCATTAAACATGAATTTAATGTCTAGGATAATTTTTAAAAG