VISDB Viral Integration Site DataBase

VIS ID

TVIS10008052

Fusion event

HBV-PCDH7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1768

Orient

-

Integrated sequence

TGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTC| |TTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCA

Chromosome

chr4

Cytoband

p15.1

Reference genome

Start

End

30940957/30939335 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-192-5p ; hsa-mir-25-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4261 ; hsa-mir-3688-3p ; hsa-mir-4789-3p ; hsa-mir-8076 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-6720-5p ; hsa-mir-1277-5p ; hsa-mir-6512-3p ; hsa-mir-190a-3p ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-5011-5p

Nearest miRNA

hsa-mir-12113/Upstream/2119667; hsa-mir-1243/Downstream/5487031;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/216115, chr4-CpG: 100/Downstream/5304674

Upstream sequence

tgtgaagtctagttacctagagcccactgtgctatgaggaagtccaaattagtctcatggaaaggccatgtTGGAAGAGAAAGAGAATGTCATTCTCCAC

Downstream sequence

TTCTGTCCTTGGCTTCTGTATTGCTTGCTATAATAAAGTCCTTGTGATACTACTGGTAATAAACTTTCATGGATGCAATCCAAGATAGACCCTACTGATA