VISDB Viral Integration Site DataBase

VIS ID

TVIS10008062

Fusion event

HBV-FGFR1OP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1823

Orient

-

Integrated sequence

TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA

Chromosome

chr6

Cytoband

q27

Reference genome

Start

End

167426119/167012631 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-340-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-32-3p ; hsa-mir-651-3p ; hsa-mir-583 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-891b ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-203a-3p ; hsa-mir-8485 ; hsa-mir-451b ; hsa-mir-3942-3p ; hsa-mir-4696 ; hsa-mir-205-3p ; hsa-mir-6502-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-1288-3p ; hsa-mir-6778-3p ; hsa-mir-1205 ; hsa-mir-4740-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-509-5p ; hsa-mir-4418 ; hsa-mir-509-3-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6781-5p ; hsa-mir-6877-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-383-3p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-3670 ; hsa-mir-6868-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-130b-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-877-3p ; hsa-mir-3675-3p ; hsa-mir-377-5p ; hsa-mir-4293 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4684-5p ; hsa-mir-548c-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-6771-3p ; hsa-mir-1250-3p ; hsa-mir-129-5p ; hsa-mir-153-5p ; hsa-mir-627-5p ; hsa-mir-8055 ; hsa-mir-8081 ; hsa-mir-924 ; hsa-mir-937-5p

Nearest miRNA

hsa-mir-10398/Upstream/14719; hsa-mir-4644/Downstream/3318130;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/12697, chr6-CpG: 17/Downstream/161235

Nearest cancer related gene

FGFR1OP(OG, No orient, 0)

Upstream sequence

gggttcaagcgattctcctgcctcagcctccctagtagctgggattacaggcatgtgccaccacgcccagctaattttgtaatttttttttagtagagat

Downstream sequence

CTATATATAATGTATGTCTTCAGGGTAAAATATTAAAGTCTATTTTACGTACTCTTATTCTCCCTACATACATTTTAAGATCTAAGAATTATAATGAGAA