VISDB Viral Integration Site DataBase

VIS ID

TVIS10008064

Fusion event

HBV-PPARD integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2232

Orient

-

Integrated sequence

AGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTT| |GGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTC

Chromosome

chr6

Cytoband

p21.31

Reference genome

Start

End

35365289/35397512 (Hg38)

Orient

+

Location type

UTR5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-mir-29b-3p ; hsa-mir-218-5p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-205-3p ; hsa-mir-302c-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-4276 ; hsa-mir-511-3p ; hsa-mir-520f-3p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-1236/Upstream/1156776; hsa-mir-10398/Downstream/72996;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/54603, chr6-CpG: 81/Downstream/54725

Upstream sequence

CGGTTGCTGTAAGTTACCTGACCTACCTGTACAGTTTGCAATGGGACCTGCCCTTGGACAGGGCCACTTGGAGGACTTTCATGGTACATACACTGCATTA

Downstream sequence

GGAGTGGTCTGGAAAGCAGGGTCAGATACCCCTGGAAAACTGAAGCCCGTGGAGCAGTGATCTCTACAGGACTGCTTCAAGGTGCGTGGTGAACAGACGT