VISDB Viral Integration Site DataBase

VIS ID

TVIS10008072

Fusion event

HBV-CHIC1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1712

Orient

-

Integrated sequence

GAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCA| |AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGC

Chromosome

chrX

Cytoband

q13.2

Reference genome

Start

End

72792334/73572498 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-5092 ; hsa-mir-223-5p ; hsa-mir-4461 ; hsa-mir-4693-3p ; hsa-mir-6867-5p ; hsa-mir-4266 ; hsa-mir-4433b-3p ; hsa-mir-513a-3p ; hsa-mir-590-3p ; hsa-mir-1200 ; hsa-mir-513c-3p ; hsa-mir-3163 ; hsa-mir-4324 ; hsa-mir-4282 ; hsa-mir-3606-3p ; hsa-mir-4793-5p ; hsa-mir-548aw ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-1264 ; hsa-mir-6882-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-561-3p ; hsa-mir-4519 ; hsa-mir-6838-5p ; hsa-mir-324-5p ; hsa-mir-3680-3p ; hsa-mir-5705 ; hsa-mir-5739 ; hsa-mir-5091 ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-6730-3p ; hsa-mir-3660 ; hsa-mir-544b ; hsa-mir-3200-5p ; hsa-mir-651-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p

Nearest miRNA

hsa-let-7f-2/Upstream/3549575; hsa-mir-105-1/Downstream/645879;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/9169, chrX-CpG: 41/Downstream/532831

Nearest cancer related gene

CHIC1(OG, No orient, 0)

Upstream sequence

gcattttgggaggctgaggccggtggatcacttgagcctaggggttcacgaccagcctgggcaacatggtgaaaccccctctgtaaacaaatataaaact

Downstream sequence

aaattgtagttctgtttttgattctttgagaaatctccaaactgctttctacagtagctgaaataatttaaattcccaccaatgttgtataagtgtcctc