Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008078
Fusion event
HBV-RELL1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
348
Orient
+
Integrated sequence
TCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCT| |TGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTC
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
Start
End
37604183/37602561 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/360570; hsa-mir-1243/Downstream/1265471;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/148605, chr4-CpG: 121/Downstream/83218
Upstream sequence
GCCTGCCTCTCTCCTGCTGGGGCCATATCCCGTCCTTCTGGTCACACTGCCTTTCATGTTACACCGCTCCTTGATGTGCTGATTCCATGGCATTCCTCTT
Downstream sequence
CTCTGATCAGCCGTGGGGGATGGACGCATGTAGACCCTTCACCAAGTTACCAAACATGCCGCTTACAGCAGTCGCGCCCTCGGTAGGGGTGGATGAGAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.