VISDB Viral Integration Site DataBase

VIS ID

TVIS10008079

Fusion event

HBV-KCNK2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1538

Orient

+

Integrated sequence

GGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTT| |TACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAAT

Chromosome

chr1

Cytoband

q41

Reference genome

Start

End

215317844/215144501 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-4753-3p ; hsa-mir-6809-3p ; hsa-mir-4284 ; hsa-mir-3682-3p ; hsa-mir-5571-5p ; hsa-mir-24-3p ; hsa-mir-4729 ; hsa-mir-4760-5p ; hsa-mir-5696 ; hsa-mir-8061

Nearest miRNA

hsa-mir-101-1/Upstream/3066816; hsa-mir-1182/Downstream/4973352;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/61208, chr1-CpG: 76/Downstream/422663

Upstream sequence

TCAGGTGGGTTGGCTGTCACTTGCTTTCTCTCTCCTGTCTGAGACAGACAGTAGTTGATGAGTTTTGAATTGCTACCACAAGGTAATAGTCAAGGCACGG

Downstream sequence

CTCGTTCCTTACACCCTTATTTCAAGTAAAATTATATTCAATATAGACAGTCAGTACTTGAAAACCTTGAGTTTTATCTCTTCAATCTATTCTGCCTTAT