VISDB Viral Integration Site DataBase

VIS ID

TVIS10008080

Fusion event

HBV-ESRRG integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2139

Orient

+

Integrated sequence

GCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCA| |GCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAG

Chromosome

chr1

Cytoband

q41

Reference genome

Start

End

216976156/216802814 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-205-5p ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6815-3p ; hsa-mir-2115-5p ; hsa-mir-5580-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-935 ; hsa-mir-320a

Nearest miRNA

hsa-mir-101-1/Upstream/4725129; hsa-mir-1182/Downstream/3315039;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/201422, chr1-CpG: 29/Downstream/286842

Upstream sequence

CCAGTTAAATATCCCCCATTTATCAAaatgatgaccaagaagcacttaatatgtgctaagcaccaggctgggaacttaattcacttaattttctcagcaa

Downstream sequence

atctatgagctagatattagtatccccacttatagattataaaaccaaagttaagagaggaaaagcaaTACTAAAAGGAAAAGTGATTTTACATATCTTG