VISDB Viral Integration Site DataBase

VIS ID

TVIS10008081

Fusion event

HBV-KIF26B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1799

Orient

-

Integrated sequence

GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

245528355/245365053 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4530 ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-634 ; hsa-mir-629-3p ; hsa-mir-3944-3p ; hsa-mir-627-3p ; hsa-mir-6795-3p ; hsa-mir-4279 ; hsa-mir-501-5p ; hsa-mir-20a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2018798; hsa-mir-3124/Downstream/1836914;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/29137, chr1-CpG: 17/Downstream/212638

Upstream sequence

GGGGCTGGAACCCTTCTGTGTCCGTGGGAAAATAGGAATCTATTGATGGATATGGCTCTTTGGCTTAAAGTgaaaaatcatgaactggtggtcaagaaat

Downstream sequence

ctaggcatagtccacgcttttaaccctctgggacctGTTTTTCTGTAAACTGAGGTGACGCTCTGTTCTGGAACAGCCCCTAAGGGGCCGTTTCAGGTCC