Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008083
Fusion event
HBV-GJB3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2081
Orient
+
Integrated sequence
TACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCT| |TTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATG
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
Start
End
35248674/34783073 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12136/Upstream/113379; hsa-mir-101-1/Downstream/2378490;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1075, chr1-CpG: 26/Downstream/1744
Upstream sequence
agcaagaccaagttgacattctagagggggagccagataattaataagaccaaaaaaaaaggacaaattctttaatttcagatagtgactaagtgctata
Downstream sequence
aagaaaaCAGAGGGGGCTGGaaaaattaggtgggcatagtggtgtgcacctgtggtcccagctacgtgggaggctgaggtaggaggctcccttgagcctg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.