Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008087
Fusion event
HBV-TCERG1L integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1825
Orient
-
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
End
132902721/131104458 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-107/Upstream/141790; hsa-mir-202/Downstream/2143053;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/9033, chr10-CpG: 25/Downstream/155617
Upstream sequence
AGAAAGATATTCAATAGAGTTGCTGTTAGCGTCTAATGCTAAGCCTGAAGCCGCCCTGAAATGATCCACAGTTAAAAACAAATGAACAACAAAAACCAGC
Downstream sequence
ATTAAAGTACAATAGATTCCGTGATGTGGTGCAGTATAAGTGTTAGACATGTCAGATGCTCCAAGAAAACCAATACTAGAACATCAGAAAATTTAATTTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.