VISDB Viral Integration Site DataBase

VIS ID

TVIS10008089

Fusion event

HBV-FAM107B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2098

Orient

+

Integrated sequence

ACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAA| |TGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCA

Chromosome

chr10

Cytoband

p13

Reference genome

Start

End

14745067/14703068 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-3942-3p ; hsa-mir-759 ; hsa-mir-5197-3p ; hsa-mir-6882-5p ; hsa-mir-6507-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6507-5p ; hsa-mir-8485 ; hsa-mir-1183 ; hsa-mir-3607-3p ; hsa-mir-4311

Nearest miRNA

hsa-mir-1265/Upstream/266407; hsa-mir-107/Downstream/3142039;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/98362, chr10-CpG: 125/Downstream/134702

Upstream sequence

atgtttatctctcaggctcattcagtttccaaaaagaactatttacaagttaatctctattcccccacccattcattctcccaggtaatcaggtattgcc

Downstream sequence

cctcaaccaaagtacctatattccccatctctccctcccctctgaggtaaggccacaaaggttgggccccaatgggatatgggatcatcactgtggctct