VISDB Viral Integration Site DataBase

VIS ID

TVIS10008093

Fusion event

HBV-DLAT integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1782

Orient

-

Integrated sequence

TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT

Chromosome

chr11

Cytoband

q23.1

Reference genome

Start

End

111923542/112052818 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-10b-5p ; hsa-mir-8085 ; hsa-mir-5192 ; hsa-mir-6731-5p

Nearest miRNA

hsa-mir-10392/Upstream/539303; hsa-let-7a-2/Downstream/1397205;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/27095, chr11-CpG: 28/Downstream/21516

Upstream sequence

ctttgtagagtttgatctccaggatctccagcctacatctccctcccctttcccttaggtcagtgggtagagctaaaagttccaactctctaatcctcta

Downstream sequence

gtcattttgacccttccagtgactggcgccatcccgaggttacttagggatcccaccctaagtatccgtcatggagcttattatataagggctcattata