VISDB Viral Integration Site DataBase

VIS ID

TVIS10008095

Fusion event

HBV-C11orf44 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1861

Orient

+

Integrated sequence

AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA| |CTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCC

Chromosome

chr11

Cytoband

q24.3

Reference genome

Start

End

130544269/130674374 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-3611 ; hsa-mir-548aw ; hsa-mir-203b-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4539 ; hsa-mir-146a-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4714-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p

Nearest miRNA

hsa-let-7a-2/Upstream/7571; hsa-mir-4697/Downstream/3224130;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/127171, chr11-CpG: 71/Downstream/241842

Nearby gene

ADAMTS15(-197730) ; SNX19(+201497) ;

Upstream sequence

TTATTATAAAGCTAAGAGTTAACATTGAAATGTGAGCAAACATGGACAGagatggatgtgttacacatgttttctcccaatgtgtagcttgtcttatttt

Downstream sequence

cttaacaatgttttccaaagactaaaagcctttcattttgatgaagtccaatttatcgcttttctcttttctaagtcatgttttctgtgtcatatctaag