VISDB Viral Integration Site DataBase

VIS ID

TVIS10008098

Fusion event

HBV-PRR5L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1829

Orient

+

Integrated sequence

GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT

Chromosome

chr11

Cytoband

p13

Reference genome

Start

End

36365876/36344326 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-502-5p ; hsa-mir-27b-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125

Nearest miRNA

hsa-mir-1343/Upstream/334122; hsa-let-7a-2/Downstream/7215330;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/399422, chr11-CpG: 122/Downstream/32077

Upstream sequence

aaaaaTCacatgctcatagaaaaatcagaaaatatataaatgtatgaaatagtctaattccactactcacagaaaatcatgttaagtcttggtgtattac

Downstream sequence

ttccagacctatttccatgcacatttagttgagattgcactgtatttacagttttgtgttttgcttccttaacatgttataaatatttcttgatattatt