Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008118
Fusion event
HBV-LRRC49 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1726
Orient
-
Integrated sequence
CGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT| |AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
Start
End
71338712/71046373 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/966905; hsa-mir-11181/Downstream/1540844;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/154023, chr15-CpG: 103/Downstream/68944
Upstream sequence
actgctttccacagtggctggactaatttaattatattcccaccagcagtgtatgagagttcctttttctccacagcctcgccagcatctgttgtttttt
Downstream sequence
cactttttagtaatagccattctaactggtgtgagatggtatctcactgtggttttgatttgcatttctctgatgattagtgatgctgagcactatttca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.