VISDB Viral Integration Site DataBase

VIS ID

TVIS10008127

Fusion event

HBV-GPATCH8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2333

Orient

+

Integrated sequence

GAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCC| |GGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAA

Chromosome

chr17

Cytoband

q21.31

Reference genome

Start

End

42473704/44396336 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-19b-3p ; hsa-mir-302c-5p ; hsa-mir-655-3p ; hsa-mir-543 ; hsa-mir-3143 ; hsa-mir-374c-5p ; hsa-mir-3613-3p ; hsa-mir-552-5p ; hsa-mir-2053 ; hsa-mir-569 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6828-5p ; hsa-mir-1183 ; hsa-mir-8084 ; hsa-mir-4506 ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-5582-5p ; hsa-mir-548an ; hsa-mir-124-3p ; hsa-mir-2355-3p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-7977 ; hsa-mir-4433a-5p ; hsa-mir-545-3p ; hsa-mir-4307 ; hsa-mir-548p ; hsa-mir-33a-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-223-3p ; hsa-mir-4328

Nearest miRNA

hsa-mir-1180/Upstream/188497; hsa-mir-10226/Downstream/538282;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/10125, chr17-CpG: 72/Downstream/106673

Upstream sequence

CCCCAGACAATCACCAAATCTCACTGCTTCCAGACAATAAAGCTGTTGAATCCCCTCCTTCTCCTCTGTGGGGTCTACCTGTTTCTCTGTGTAAAACAGC

Downstream sequence

AAAAGTACATGAGGGAGACTGTTAAAGATGAGCATCCCTCAGAAGCCCCCAGCTGACTGCTGCCCATTAGCTCAAAAATCCCAATACTGGGGGCACTACA