Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008130
Fusion event
HBV-ARSG integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1837
Orient
+
Integrated sequence
GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCC| |TAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTAC
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
Start
End
66412426/68416285 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10226/Upstream/944700; hsa-mir-1250/Downstream/8166;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/123894, chr17-CpG: 70/Downstream/40923
Upstream sequence
atttagagctccttttagcagttcttgtagtggtgacttggtagtggtgaattttctcagcatttgtttgtatccttctttcatatatgacgcttatttt
Downstream sequence
tgctggatacagaattcttggctgataattgttttgatggaggaggctgaagatatggccccagtcctttctagcttgtagggtatctgctgttaatcct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.