VISDB Viral Integration Site DataBase

VIS ID

TVIS10008136

Fusion event

HBV-DDX18 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1818

Orient

+

Integrated sequence

GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT

Chromosome

chr2

Cytoband

q14.1

Reference genome

Start

End

118575835/117818259 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-324-3p ; hsa-mir-128-3p ; hsa-mir-99a-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/4096891; hsa-mir-10b/Downstream/9605278;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/3208, chr2-CpG: 49/Downstream/17804

Upstream sequence

GAAAAGGAAGGAATGTTTTTTGAAGATGATGGAATTTCAGTAAGCTCGGATGAAAGAATGGACATTATAATTGAGATTTGTATAAGCAGAGATATCAAGG

Downstream sequence

TAGGATAAGATaggggtcagcaaactatccctccttctacctgtttttgtaaataaagttttactgggtcatagcaatgcctatttggttgtgtttatgg