VISDB Viral Integration Site DataBase

VIS ID

TVIS10008144

Fusion event

HBV-ATG7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1829

Orient

+

Integrated sequence

GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT

Chromosome

chr3

Cytoband

p25.3

Reference genome

Start

End

11497854/11456380 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-320c ; hsa-mir-96-5p ; hsa-mir-4687-5p ; hsa-mir-4726-5p ; hsa-mir-6749-3p ; hsa-mir-4640-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-4733-3p ; hsa-mir-6895-5p ; hsa-mir-6753-5p ; hsa-mir-4708-3p ; hsa-mir-6826-5p ; hsa-mir-3922-5p ; hsa-mir-451b ; hsa-mir-4753-5p ; hsa-mir-154-5p ; hsa-mir-3127-5p ; hsa-mir-6802-3p ; hsa-mir-6879-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6783-5p ; hsa-mir-4640-3p ; hsa-mir-34a-5p ; hsa-mir-210-3p ; hsa-mir-106a-5p

Nearest miRNA

hsa-mir-12127/Upstream/1061818; hsa-let-7g/Downstream/4039859;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/183929, chr3-CpG: 38/Downstream/31930

Upstream sequence

taataagatcctgaccctcatgtagGGCTGGGAAGTATAACTGGAAAGGGAGGCTAAGAgtggcagatgctgtgatgtggcactctggtctccctctggt

Downstream sequence

tcagttggtaggcatctggattgtttccacttttttgctgttatgaattatgctgctgtgaacattcgtgtacaagttgttgtatgaagtacacgttttt