Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|
Integrated sequence
TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG
End
144068067/143146914 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/17639607; hsa-mir-1305/Downstream/196546;
Nearest cancer related gene
Upstream sequence
TGTGAATCACAATGTAGCAGAGGCAGACCAAGCATTACATTATTATTTAGAGCTGGACTGCACCAATTACTTGTCCTCGTGCCAAAGGCAAATATGTTTG
Downstream sequence
gggaagattaccttcccactccatctccttttcagctccccttccttcctgctgagagccactttcatcaacaataaaaatctcctgcacttaccatgtc
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.