Basic Information
VIS ID
TVIS10008152
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1859
Orient
+
Integrated sequence
TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
End
144068067/143146914 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/17639607; hsa-mir-1305/Downstream/196546;
Nearby gene
INPP4B(-300463) ; USP38(+38003) ;
Nearest cancer related gene
INPP4B(TSG, -300463) ;
Upstream sequence
TGTGAATCACAATGTAGCAGAGGCAGACCAAGCATTACATTATTATTTAGAGCTGGACTGCACCAATTACTTGTCCTCGTGCCAAAGGCAAATATGTTTG
Downstream sequence
gggaagattaccttcccactccatctccttttcagctccccttccttcctgctgagagccactttcatcaacaataaaaatctcctgcacttaccatgtc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate