VISDB Viral Integration Site DataBase

VIS ID

TVIS10008170

Fusion event

HBV-NDST1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2457

Orient

+

Integrated sequence

AGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTAT| |TCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACAT

Chromosome

chr5

Cytoband

q33.1

Reference genome

Start

End

149918016/150538454 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-191-5p ; hsa-mir-375 ; hsa-mir-296-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-24-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-4528 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-410-3p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1972 ; hsa-mir-1306-5p ; hsa-mir-4690-5p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-128-3p

Nearest miRNA

hsa-mir-10397/Upstream/805564; hsa-mir-103a-1/Downstream/983633;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/10329, chr5-CpG: 23/Downstream/86654

Upstream sequence

ccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccct

Downstream sequence

agcagcttggaccagggcccaatgttgggatgtggccatactctgggcttagaatagttaggcctgtggttagatgagttagatatagggtgtgggagga