VISDB Viral Integration Site DataBase

VIS ID

TVIS10008176

Fusion event

HBV-HIVEP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2610

Orient

+

Integrated sequence

CTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGT| |TAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCA

Chromosome

chr6

Cytoband

q24.2

Reference genome

Start

End

143140257/142819120 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-130b-3p ; hsa-mir-598-3p ; hsa-mir-484 ; hsa-mir-10b-5p ; hsa-mir-136-5p ; hsa-mir-298 ; hsa-mir-5684 ; hsa-mir-5700 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4662a-3p ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-302c-3p ; hsa-mir-372-3p ; hsa-mir-520e ; hsa-mir-520b ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p

Nearest miRNA

hsa-mir-10398/Upstream/2135237; hsa-mir-1202/Downstream/8283555;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/516804, chr6-CpG: 60/Downstream/107552

Upstream sequence

ttcagccaatgtcactcagccaggctcagaactgggCTGCAGTGACCACCAGCCTAGTGTTCTGTGCACCCCGCCAGGCTCCTAGGGGAACAGGACAAAG

Downstream sequence

ccacttgggaggctgaggcaggagggttgcttgagcccaggatgcaatgagctatgatcactccactgctcttcaggctgggcaacagagtgagaccctg