Basic Information
VIS ID
TVIS10008212
Fusion event
HBV-chrX integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1203
Orient
-
Integrated sequence
CCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCA| |CTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCG
Host Sequence
Chromosome
chrX
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
52569306/52540296 (Hg38)
End
52569306/52540296 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1587/Upstream/203654; hsa-let-7f-2/Downstream/655115;
Nearest TSS
ENST00000429181/Upstream/19493; ENST00000288839/Downstream/114604;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/277967, chrX-CpG: 65/Downstream/356563
Nearby gene
XAGE1B(-23109) ; SSX8P(+82679) ;
Upstream sequence
ttttccatacagatctgatcttatcacctttgtttaaaacacttcaaagaccttcaagaaaaaaattaaactctttaacatgattttcaaggcccttcat
Downstream sequence
TGGAGGCTTTGCTTGGGCTGCAGCATACGTGAATGTTATGCATTTCCTGCATTCATGGAGACCTCCCTGTGAGTGCACAGGGACCTCCATTCCCCTACGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate