Basic Information
VIS ID
TVIS10008213
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1785
Orient
-
Integrated sequence
CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG| |TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
16134064/14022184 (Hg38)
End
16134064/14022184 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/542918;
Nearest TSS
ENST00000430575/Upstream/35671; ENST00000250823/Downstream/34033;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/269230, chrY-CpG: 22/Downstream/501675
Nearby gene
VCY(-35672) ;
Upstream sequence
ttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttag
Downstream sequence
aaggtaggtggatcacgaggtcaagagatcgagaccatcctggccaacatggtgaaaccccgtttctactacaaatacaaaaattagccagatgtggtgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate