VISDB Viral Integration Site DataBase

VIS ID

TVIS10008217

Fusion event

HBV-CCNY integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

314

Orient

+

Integrated sequence

TCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTC| |GCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATC

Chromosome

chr10

Cytoband

p11.21

Reference genome

Start

End

35788485/35499557 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7b-5p ; hsa-mir-744-5p ; hsa-mir-93-3p ; hsa-mir-193b-3p ; hsa-mir-4669 ; hsa-mir-6516-5p ; hsa-mir-6751-5p ; hsa-mir-6803-5p ; hsa-mir-455-3p ; hsa-mir-4497 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6499-3p ; hsa-mir-6835-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4795-5p ; hsa-mir-1296-3p ; hsa-mir-298 ; hsa-mir-4696 ; hsa-mir-1252-5p ; hsa-mir-186-3p ; hsa-mir-922 ; hsa-mir-4733-5p ; hsa-mir-3613-3p

Nearest miRNA

hsa-mir-1265/Upstream/419877; hsa-mir-107/Downstream/141615;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/161945, chr10-CpG: 75/Downstream/108033

Upstream sequence

gagatttgggtggggacacagccaaaccatatcaGCTTTCTTGGTCGGACTTATAGTCAGAACTATTGAAGGTTATGCATCTCAGCCATTACTTCTACAC

Downstream sequence

GTGAATAATTCCTAATCTTCTCAATAGTACCCATATAGGAAGTGCTGGTATTTTTTGAGGCATGGATATCTTTCATTTGCTGAAGGCAGGGGCTGATGTA