VISDB Viral Integration Site DataBase

VIS ID

TVIS10008218

Fusion event

HBV-ADAMTS14 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1736

Orient

+

Integrated sequence

ATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGG| |AGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGC

Chromosome

chr10

Cytoband

q22.1

Reference genome

Start

End

72510758/70751002 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-4314 ; hsa-mir-6845-5p ; hsa-mir-6762-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-3926 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p

Nearest miRNA

hsa-mir-1265/Upstream/3347592; hsa-mir-107/Downstream/1039745;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/78020, chr10-CpG: 73/Downstream/64755

Upstream sequence

agaacagaggggcaaatctttatgaccttagattcttagatacgacaggcactaaaagcatacacagcaaaagaaaaaatagataaattggacttcatca

Downstream sequence

agattgaaaacttaagtgcatcaaaagacattatcaaggaaaggaaaagaccacctgcagaatgggggaaaatacttgcaagtcatatatttgatgaggg