VISDB Viral Integration Site DataBase

VIS ID

TVIS10008220

Fusion event

HBV-MYO16 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2193

Orient

+

Integrated sequence

ACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTC| |AGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAG

Chromosome

chr13

Cytoband

q33.3

Reference genome

Start

End

109251700/108599352 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4695-3p ; hsa-mir-602 ; hsa-mir-8485 ; hsa-mir-548b-3p ; hsa-mir-3133

Nearest miRNA

hsa-mir-1267/Upstream/1068104; hsa-mir-4502/Downstream/1741606;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/102681, chr13-CpG: 22/Downstream/527983

Upstream sequence

tgggttggttccaagtctttgctattgtgaatagtgccgcaataaacatacatgtgcatgtgtctttatagcagcatgatttatagtcctttgggtatat

Downstream sequence

acccagtaatgggatggctgggtcgaatggtgtttctagttctagatccctgaggaatcgccacactgacttccacaatggttgaactagtttaccgtcc