VISDB Viral Integration Site DataBase

VIS ID

TVIS10008221

Fusion event

HBV-chr13 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1817

Orient

-

Integrated sequence

TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT

Chromosome

chr13

Cytoband

q13.3

Reference genome

Start

End

36833710/36259573 (Hg38)

Orient

+

Location type

Intronic

Target gene

CCDC169 ; CCDC169-SOHLH2

miRNAs that regulate target gene

hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-4639-5p ; hsa-mir-3941 ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-708-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-3121-3p

Nearest miRNA

hsa-mir-2276/Upstream/12097069; hsa-mir-1267/Downstream/3404461;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/44672, chr13-CpG: 33/Downstream/37957

Upstream sequence

caggcttaagtaagtggctcaagaggtctgagtatgttccctggggttattaactaaaagaacttgataacaccctttagaggtttccaattggttacac

Downstream sequence

actatgcaaatgaagacagcccacgaccaaccagaggctgaagacatggcctgcaatcaatcagaggctgaagtggagttacactctatgcaaatgaagg