Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008240
Fusion event
HBV-EYA2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2690
Orient
+
Integrated sequence
TTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGG| |GTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGA
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
Start
End
45755870/47127231 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/1422051; hsa-mir-1-1/Downstream/39736;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/231850, chr20-CpG: 38/Downstream/111679
Upstream sequence
aCTTAGTGAATTTGTTAACCAGGCCACCAGAAATTCTTCAGAAACACATCTAAAGTGCCACTAACTGTTCTCAACTGAACAGTTAGTTACGGATGAAATT
Downstream sequence
GTTAGTACAAGAATATTTGAAGACAGTCCCCAAATTCCCAAACATCTACCTCTACTTATTATGCAAGTTTCCTTAAGAAAATGCTTATGTggccaagctc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.