VISDB Viral Integration Site DataBase

VIS ID

TVIS10008245

Fusion event

HBV-ADH1B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2644

Orient

+

Integrated sequence

TCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCT| |GCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGAC

Chromosome

chr4

Cytoband

q23

Reference genome

Start

End

100241743/99320586 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4758-3p ; hsa-mir-3189-5p ; hsa-mir-5699-5p ; hsa-mir-5011-5p ; hsa-mir-4280 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4705 ; hsa-mir-4666a-3p ; hsa-mir-5580-3p ; hsa-mir-34b-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-3149 ; hsa-mir-297 ; hsa-mir-568 ; hsa-mir-3924 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p

Nearest miRNA

hsa-mir-12113/Upstream/323126; hsa-mir-1243/Downstream/1920209;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/231608, chr4-CpG: 40/Downstream/242984

Upstream sequence

gagcagaggccAGAAAGGCAGGTCAGGCCAGATCATGTAGTAGGGCCATGGAAAGGAGTGCCCTTGTGTGTTTTAAGTTAGAATCAAATGTTTTGAGAGT

Downstream sequence

AGAAGAAAAAACCAAATATCTGTATTCCTAGTGCTAAGTGATTCAAATTGTATTATTATTCAAATTGTATCATTGATTTTCTGTAAAACCATATTAACTT