VISDB Viral Integration Site DataBase

VIS ID

TVIS10008246

Fusion event

HBV-KIAA1109 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1786

Orient

-

Integrated sequence

AACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGT| |AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

123120092/122198937 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-219a-2-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-410-3p ; hsa-mir-497-3p ; hsa-mir-92b-3p ; hsa-mir-873-5p ; hsa-mir-4528 ; hsa-mir-5589-3p ; hsa-mir-190a-3p ; hsa-mir-340-5p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-944

Nearest miRNA

hsa-mir-12113/Upstream/7542083; hsa-mir-1305/Downstream/3308322;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/46316, chr4-CpG: 45/Downstream/180315

Upstream sequence

tgataggagcaccaaccctattataaactgcatgtggaagtgatctaggttgtgtgctccttatgagaatctaatgcctgatgatctgtcactgtttccc

Downstream sequence

ACTATATTGCTGAGAAACTGTCATTACATGAGGGGAATAGCTGTTACTtagtaaccatcattatataaggagtagttgaaaatgatgaaaatatgtaccc