Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
ATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCA| |ATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGT
End
14023155/13696660 (Hg38)
Nearest miRNA
hsa-mir-12136/Upstream/1117637; hsa-mir-101-1/Downstream/3162289;
Nearest cancer related gene
Upstream sequence
aggttatgaggatgagtgagagagtgcatgtaaaatacctagaacagagcccaacagagaataagtattGTTATCATTCGGGGAATTTGAAGTCCACTTA
Downstream sequence
TTCTCATTGGCAATGTACGGTAAACTCTTGGATCTCAGCTGTAAGATCTGCAATCTTTTTGGAAGCGCTACAGGCATTCCAGCTGCTATGCAGGGCAGGA
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.