Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008280
Fusion event
HBV-GRIA4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1765
Orient
-
Integrated sequence
TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
End
105842655/105971928 (Hg38)
Orient
-
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/2121948; hsa-let-7a-2/Downstream/5375829;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/361233, chr11-CpG: 26/Downstream/50070
Upstream sequence
CTTTGCCATGCGATTCTAATGTAGTTTTACTTGAATAACATAAAATAACATATATAATGTTATTTATGTTATTTTCCACGTGAAGAACTCCTGTAAACCT
Downstream sequence
TGCCGTTTTGAAACTCAGTGAGGCAGGCGTCTTAGACAAGCTGAAAAACAAATGGTGGTACGATAAAGGTGAATGTGGACCCAAGGACTCTGGAAGCAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.