C12orf71 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008299
Fusion event
HBV-C12orf71 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2364
Orient
+
Integrated sequence
TTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGG| |TCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGG
Host Sequence
Chromosome
chr12
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
27236556/27083623 (Hg38)
End
27236556/27083623 (Hg38)
Orient
-
Location type
Intronic
Target gene
C12orf71
Nearest miRNA
hsa-mir-1244-3/Upstream/1209544; hsa-let-7i/Downstream/15240077;
Nearest TSS
ENST00000382841/Upstream/1109; ENST00000434385/Downstream/77643;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/60713, chr12-CpG: 67/Downstream/160426
Nearby gene
C12orf71(-1101) ; STK38L(+160522) ;
Upstream sequence
atttatataaacacacatatacatatctGTACATTTATACAATATGTCCACATACACATATACATATATGTAAATGTGGATATGACATATAGTTGAAACT
Downstream sequence
GAAATTATTTTATCCCATAGCCTACAACAAACATATATATGGTTACTCTGCAATTTTTAACCACTTCTTATTAATGCtaaataaatctgtaataaacccg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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