Basic Information
VIS ID
TVIS10008306
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2355
Orient
-
Integrated sequence
TTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGA| |CGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGT
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
95433/10305 (Hg38)
End
95433/10305 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Downstream/1650010;
Nearest TSS
ENST00000382841/Downstream/27797;
Nearest CpG islands
None/Target, None/Upstream, chr12-CpG: 104/Downstream/20484
Nearby gene
WASH8P(-4170) ; FAM138D(+52513) ;
Upstream sequence
ttagggtagggttagggttagggttagggttagggtagggttagggttagggttaggggttagggttagggttagggttagggttacggtttggggttgg
Downstream sequence
ggttagggttagggttagggttaggggtagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate